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Maternal Age Specific Odds of Fetal
Down's Syndrome During the 2nd Trimester Based on Non-Structural Findings
Maternal Age |
Pre-US Odds |
Normal US Scan |
Inc. Nuchal Thickness |
Echogenic Bowel |
Short Humerus |
Short Femur |
Echogenic Intracardiac Focus |
Renal Pyelectasis |
(Years) |
(1:_) |
(1:_) |
(1:_) |
(1:_) |
(1:_) |
(1:_) |
(1:_) |
(1:_) |
20 |
1176 |
1960 |
63 |
214 |
511 |
470 |
588 |
735 |
21 |
1160 |
1933 |
62 |
211 |
504 |
464 |
580 |
725 |
22 |
1136 |
1893 |
61 |
207 |
494 |
454 |
568 |
710 |
23 |
1114 |
1857 |
60 |
203 |
484 |
446 |
557 |
696 |
24 |
1087 |
1812 |
58 |
198 |
473 |
435 |
544 |
679 |
25 |
1040 |
1733 |
56 |
189 |
452 |
416 |
520 |
650 |
26 |
990 |
1650 |
53 |
180 |
430 |
396 |
495 |
619 |
27 |
928 |
1547 |
50 |
169 |
403 |
371 |
464 |
580 |
28 |
855 |
1425 |
46 |
155 |
372 |
342 |
428 |
534 |
29 |
760 |
1267 |
41 |
138 |
330 |
304 |
380 |
475 |
30 |
690 |
1150 |
37 |
125 |
300 |
276 |
345 |
431 |
31 |
597 |
995 |
32 |
109 |
260 |
239 |
299 |
373 |
32 |
508 |
847 |
27 |
92 |
221 |
203 |
254 |
318 |
33 |
421 |
702 |
23 |
77 |
183 |
168 |
211 |
263 |
34 |
342 |
570 |
18 |
62 |
149 |
137 |
171 |
214 |
35 |
274 |
457 |
15 |
50 |
119 |
110 |
137 |
171 |
36 |
216 |
360 |
12 |
39 |
94 |
86 |
108 |
135 |
37 |
168 |
280 |
9 |
31 |
73 |
67 |
84 |
105 |
38 |
129 |
215 |
7 |
23 |
56 |
52 |
65 |
81 |
39 |
98 |
163 |
5 |
18 |
43 |
39 |
49 |
61 |
40 |
74 |
123 |
4 |
13 |
32 |
30 |
37 |
46 |
41 |
56 |
93 |
3 |
10 |
24 |
22 |
28 |
35 |
42 |
42 |
70 |
2 |
8 |
18 |
17 |
21 |
26 |
43 |
31 |
52 |
2 |
6 |
13 |
12 |
16 |
19 |
44 |
23 |
38 |
1 |
4 |
10 |
9 |
12 |
14 |
From: Nyberg DA, Luthy DA, Resta RG, Nyberg BC, Williams MA. Age-adjusted
ultrasound risk assessment for fetal Down's syndrome during the second
trimester: description of the method and analysis of 142 cases. Ultrasound
Obstet Gynecol 12:8-14, 1998.
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